ID29 is the ESRF's world-first beamline entirely dedicated to time-resolved serial macromolecular crystallography (SMX), jointly operated with the EMBL. Designed from the ground up to exploit the full potential of the ESRF Extremely Brilliant Source (EBS), the beamline expands both the scope and the nature of macromolecular crystallography experiments, opening new frontiers in structural biology.

ID29's unique capabilities allow scientists to capture molecular motions by observing time-dependent structural changes at room temperature, enabling biological processes to be visualised as molecular "movies".  Operating over an energy range of 10–15 keV with an extremely high flux density, the beamline is equipped with a Jungfrau 4M detector and supports a range of sample delivery methods, making it a versatile and powerful instrument for the life sciences community.