Synopsis
ID23-1 offers the opportunity to make highly efficient monochromatic measurements at energies from 6 Kev to 20 Kev with a flux of ~1-4 E12 photons/second and a variable beam size from 0.05 to 0.001 mm^2.
Status:
open
Disciplines
- Medicine
- Life Sciences
- Chemistry
- Environmental Sciences
Applications
- Macromolecular crystallography
Techniques
-
MX - macromolecular crystallography
-
MAD - multi-wavelength anomalous dispersion
Beam size
- Minimum (H x V) : 10.0
x 10.0
µm²
-
Maximum (H x V) : 45.0
x 30.0
µm²
Sample environments
- 100 K cryostream
- Automatic sample changer FlexHCD
Detectors
- Eiger 2 16M CdTe (Dectris)
- Rontec Xflash X-ray fluorescence detector
Technical details
ID23-1 offers diffraction data collection between energies going from 6 Kev to 20 Kev capable of MAD/SAD experiments with a variable beam size from 0.05 to 0.001 mm^2.
The ID23-1 structural biology beamline at the ESRF
Novel fluoro-brominated benzotriazoles as potential CK2 inhibitors. How does fluorination affect the properties of benzotriazoles?
Kasperowicz S., Werner C., Podsiadla-Bialoskórska M., Szolajska E., Maciejewska A.M., Lindenblatt D., Niefind K., Poznanski J., Winiewska-Szajewska M.,
Bioorganic Chemistry 169, 109446-1-109446-14 (2026)
Extending the chemical space of glutarimide-based cereblon ligands through an efficient Rh(II)-catalyzed X-H insertion reaction
Levashova E., Bischof L., Bunev A., Sapegin A., Grygor'eva O., Kudinov A., Ebeling S., Tatarinov I., Dar'in D., Kantin G., Hartmann M.D., Kalinin S.,
European Journal of Medicinal Chemistry 301, 118235-1-118235-14 (2026)
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors
Palte R.L., Mandal M., Sikorska J., Villafania A.B., Rickard M.M., Bauer R.J., Buevich A.V., Chai X., He J., Hussain Z., Koglin M., MacDonald H.B., Mansueto M.S., Maskos K., Methot J.L., Robustelli J., Soriano A., Tauchert M.J., Tyagarajan S., Zhang M., Klein D.J., Hicks J.D., McLaren D.G., Gabelli S.B., Wyss D.F.,
Nature Communications 17, 79-1-79-17 (2026)
Integrated structural dynamics uncover a new B12 photoreceptor activation mode
Rios-Santacruz R., Poddar H., Pounot K., Heyes D.J., Coquelle N., Mackintosh M.J., Johannissen L.O., Schianchi S., Jeffreys L.N., De Zitter E., Munro R., Appleby M., Axford D., Beale E.V., Cliff M.J., Davila-Miliani M.C., Engilberge S., Gotthard G., Hadjidemetriou K., Hardman S.J.O., Horrell S., Hub J.S., Ishihara K., Jaho S., Karras G., Kataoka M., Kawakami R., Mason T., Okumura H., Owada S., Owen R.L., Royant A., Saaret A., Sakuma M., Shanmugam M., Sugimoto H., Tono K., Zala N., Beale J.H., Tosha T., Colletier J.P., Levantino M., Hay S., Kozlowski P.M., Leys D., Scrutton N.S., Weik M., Schirò G.,
Nature , epub (2026)
Glutamate indicators with increased sensitivity and tailored deactivation rates
Aggarwal A., Negrean A., Chen Y., Iyer R., Reep D., Liu A., Palutla A., Xie Michael E., MacLennan Bryan J., Hagihara Kenta M., Kinsey Lucas W., Sun Julianna L., Yao P., Zheng J., Tsang A., Tsegaye G., Zhang Y., Patel Ronak H., Arthur Benjamin J., Hiblot J., Leippe P., Tarnawski M., Marvin Jonathan S., Vevea Jason D., Turaga Srinivas C., Tebo Alison G., Carandini M., Rossi L. Federico, Kleinfeld D., Konnerth A., Svoboda K., Turner Glenn C., Hasseman Jeremy P., Podgorski K.,
Nature Methods , epub (2025)
Role of the residue L254 in the substrate recognition by carboxypeptidase T from Thermoactinomyces vulgaris revealed by X-ray diffraction
Akparov V.K., Timofeev V.I., Konstantinova G.E., Kuranova I.P.,
Crystallography Reports 70, 573-582 (2025)