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#worldmalariaday The ESRF gains insight into the mechanism of antimalarial drugs

25-04-2020

The ESRF has welcomed scientists studying the malaria parasite Plasmodium falciparum for many years on several beamlines, mostly from the structural biology group, but recently researchers have started using other techniques like X-ray phase contrast and X-ray fluorescence nanoprobe on ID16A.

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At the end of last year a team published a study on the mechanism of quinoline, an effective compound in antimalarial drugs, in infected red blood cells in near-native conditions. This work, published in PNAS, was led by the Weizmann Institute and the University of Copenhagen. The team used the ESRF, Alba Synchrotron and BESSY. (click here for more information)

 

Text and video by Montserrat Capellas Espuny.

Top image: An anopheles mosquito biting a human. Credits: wehi.tv

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European Synchrotron Radiation Facility - 71, avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France.