Tribute to Sine Larsen

Throughout her remarkable career, marked by significant contributions to science, education, and international collaboration, Sine Larsen rose as an inspirational figure for generations of crystallographers and scientists all over the world.

After appointments at M.I.T. and the Danish Technical University, in 1974, Professor Larsen joined the University of Copenhagen where she became Director of the Centre of Crystallographic Studies in 1994, and Professor of Structural Chemistry in 1997. She served on several advisory committees for large facilities and on many international committees including serving as General Secretary and Treasurer of the International Union of Crystallography (IUCr) from 1996 to 2005 and as its President from 2008 to 2014.

A distinguished figure in the field of crystallography, with major contributions to both structural biology and structural chemistry, Sine Larsen was awarded the Max Perutz Prize by the European Crystallographic Association in 2018. This prestigious award highlighted her lifelong contributions to crystallography, the development of synchrotron radiation facilities in this field and her impact on the global scientific community.

Sine was not only a brilliant scientist and leader, but also a deeply caring and welcoming presence in our community. She had an infectious enthusiasm and an extraordinary ability to make people feel at home, whether they were long-time colleagues or new arrivals.

As ESRF director of Research for Life Sciences, she left an indelible mark on the ESRF, giving fundamental contributions to the ESRF programme, in particular by pushing the boundaries of structural biology and imaging techniques for life sciences. But it was her unique blend of scientific expertise and caring leadership that truly set her apart. She fostered a collaborative environment, ensuring that both established researchers and new talents had the support and encouragement to thrive. Her ability to combine scientific expertise with collaborative leadership was key in fostering international partnerships and in expanding the reach of life sciences research at the ESRF. She played a major role in the conception and development of the Partnership for Structural Biology bringing together all European Photon and Neutron Science Campus partners, and played a pivotal role in strengthening the user community, creating a vibrant environment for scientific collaboration and innovation. In the same spirit, she was a driving force in establishing a Partnership for Soft Condensed Matter.

Those who worked alongside Sine remember her as a mentor and a role model. She encouraged the next generations of scientists to push the boundaries of knowledge, nurturing curiosity, rigour, and a profound passion for science. Her colleagues at the ESRF will always remember her joy for life, enthusiasm, and dedication to the ESRF, whether as Director of Research, Nordsync delegate to the ESRF Council, or as a user.

Her legacy, both scientific and personal, is vast and enduring. In addition to her tremendous contributions to science, she touched the lives of all who had the privilege of working with her. Those of us who knew her will always cherish her warmth, constant support and the positive impact she had on our lives.

Sine’s passing is a profound loss to the ESRF and to the scientific community at large. Her work and genuine care for others continues to make a difference, inspiring and guiding us, who will always remember her fondly.

The ESRF extends its heartfelt condolences to her family, friends and all those who were close to her. Our thoughts are with them during this most difficult time.

Sine Larsen in the footbridge of the Experimental Hall. Credits: E. Bouy.

Top image: Sine Larsen at the ESRF in 2017. Credits: Etienne Bouy.