FIP2 is available to the users since 1 October 2021. Apply now for beamtime through the Soleil synchrotron interface!

The beamline FIP-BM30A ended operation on 20 November 2018 and has now been replaced by FIP2-BM07 upon ESRF-EBS upgrade.

FIP2 (French beamline for Investigation of Proteins) is located on a Bending Magnet section 07 (BM07) of ESRF. It is especially dedicated to crystallography of biological macromolecules. This beamline can be used either for standard diffraction or for multiwavelength diffraction, using anomalous dispersion.

Its optics can deliver a focused beam on a fixed sample position, with an energy resolution of about 2.e-4 in a large accessible energy range (7-17 keV now, 5 to 25 keV in a near future). The beam size is around ~60×230 µm VxH at 12.6 keV.

FIP2-BM07 offers the following capabilities:

  • High throughput screening of frozen crystal (G-Rob sample changer).
  • Data collection at fixed wavelength.
  • Anomalous diffraction experiments.
  • In situ (in plate) crystal screening and data collection (to be implemented during spring 2022).
  • X-ray fluorescence spectroscopy (to be implemented during 2022).
  • On-line UV-Vis absorption spectroscopy, with a microspectrophotometer (to be implemented during 2022).
  • Humidity controlled experiments.
  • High pressure experiments.

The FIP2 sample storage dewar is currently set for SC3-SPINE standard only, but will be upgraded to host Unipuck standard as well (end of 2022).

The beamline control is now performed by the well-known "MxCube" interface to be consistent with other similar beamlines around the world. Data is automatically uploaded and analysed by the ESRF "ISPyB" system.