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Targeting autocrine retinoic acid signaling by ALDH1A2 inhibition enhances antitumor dendritic cell vaccine efficacy
Fang C., Esposito M., Hars U., Byrne R.T., Song B., Huang J., Roichman A., Shue L., Cheng X., Proudfoot J., Zhao D., Wei Y., Cristea I.M., Rabinowitz J.D., Kang Y.,
Nature Immunology , epub (2026)
Shaping and stabilizing the active phase: The role of carbon surface defects in carbon-supported Co Fischer-Tropsch synthesis catalysts
Herold F., Goemans M.J.A., Cautaerts P., Etzold B.J.M., Rønning M.,
ACS Catalysis 16, 446-463 (2026)
Interaction of Staphylococcus aureus di‐iron Repair of Iron Centers protein with the iron–sulfur cluster assembly SUF system
Lourenco F.M., Silva L.S.O., Almeida M.R., Folgosa F., Matias P.M., Carvalho S.M., Lima J.C., Romão C.V., Saraiva L.M.,
Protein Science 35, e70406-1-e70406-14 (2026)
Transition from fracture propagation to coalescence in westerly granite during the preparation process of macroscopic failure
McBeck J., Cordonnier B., Zhu W., Renard F.,
Journal of Geophysical Research: Solid Earth 131, e2025JB032676-1-e2025JB032676-25 (2026)
Linking surface reconstructions to catalytic selectivity on Pt(100) during ammonia oxidation
Simonne D., Coati A., Vlad A., Garreau Y., Voisin B., Richard M. I., Resta A.,
ACS Catalysis 16, 599-613 (2026)
Glutamate indicators with increased sensitivity and tailored deactivation rates
Aggarwal A., Negrean A., Chen Y., Iyer R., Reep D., Liu A., Palutla A., Xie Michael E., MacLennan Bryan J., Hagihara Kenta M., Kinsey Lucas W., Sun Julianna L., Yao P., Zheng J., Tsang A., Tsegaye G., Zhang Y., Patel Ronak H., Arthur Benjamin J., Hiblot J., Leippe P., Tarnawski M., Marvin Jonathan S., Vevea Jason D., Turaga Srinivas C., Tebo Alison G., Carandini M., Rossi L. Federico, Kleinfeld D., Konnerth A., Svoboda K., Turner Glenn C., Hasseman Jeremy P., Podgorski K.,
Nature Methods , epub (2025)
Magnetic excitations of a half-filled Tl-based cuprate
Bialo I., Wang Q., Küspert J., Hong X., Martinelli L., Gerguri O., Chan Y., von Arx K., Forslund O.K., Pudelko W.R., Lin C., Plumb N.C., Sassa Y., Betto D., Brookes N.B., Rosmus M., Olszowska N., Watson M.D., Kim T.K., Cacho C., Horio M., Ishikado M., Rønnow H.M., Chang J.,
Communications Materials , epub (2025)
Discovery of BI-2493, a pan-KRAS inhibitor showing in vivo efficacy
Broker J., Waterson A.G., Hodges T.R., Abbott J.R., Arnold A., Böttcher J., Braun N., Cui J., Fuchs J.E., Gerstberger T., Gogg S., Hanner S., Herdeis L., Howell L.W., Mantoulidis A., Mayer M., Phan J., Rocchetti F., Sankar K., Sarkar D., Schaaf O., Sensintaffar J.L., Sun Q., Wunberg T., Fesik S.W.,
Journal of Medicinal Chemistry 68, 15649-15668 (2025)
Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1
Cocomazzi P.G., Iatrou A., Minici C., Gounari M., Linder A.T., Akpinaroglu C., Patrone M., Broggini L., Frenquelli M., Sarrigeorgiou I., Lymberi P., Petrakis G., Koletsa T., Scarfò L., Agathangelidis A., Jumaa H., Maity P.C., Ghia P., Stamatopoulos K., Degano M.,
Nature Communications , epub (2025)
Cellular potency optimization of novel heme-binding imidazo[5,1-b]thiazoles, imidazo[1,5-a]pyridines and pyrazines as potent IDO1 inhibitors devoid of cytochrome P450 inhibition
Cren S., Lotz-Jenne C., Kimmerlin T., Pothier J., Risch P., Mac Sweeney A., Joesch C., Pouzol L., Chavanton-Arpel A., Boss C.,
Journal of Medicinal Chemistry 68, 20130-20153 (2025)
Magnetic phase transition in the quasi-one-dimensional spin chain system Fe0.75Cu0.25NbO4
da Silva Evaristo D., Santos Silva Jr R., Figueredo Jucá R., dos Santos C., Saraiva G.D., Gainza J., Rodrigues J.E., Céspedes E., Martínez J.L., Alonso J.A., Frota de Vasconcelos I., Sampaio Oliveira F., dos Santos Ferreira N., Ramiro de Castro A.J., Passamani E.C., Macedo M.A.,
ACS Omega 10, 62645-62656 (2025)
Polo-like kinase 1–inhibitor co-complex structures via the surface-entropy reduction approach and a DARPin-assisted approach
Eberspaecher U., Schmitz Arndt A., Siemeister G., Bömer U., Bandeiras Tiago M., Matias Pedro M., Schulze Volker K., Hillig Roman C.,
Acta Crystallographica D 81, 718-733 (2025)
Investigation on process stability and repeatability of flow properties and topography of PBF-LB/M manufactured channels
Findeklee P., Schurb J., Gerber J., Kreutzer A., Polte J.,
Progress in Additive Manufacturing , epub (2025)
From pharmacophore to warhead: NAD+‐targeting triazoles as mechanism‐based sirtuin inhibitors
Friedrich F., Meleshin M., Papenkordt N., Gaitzsch L., Prucker I., Borso M., Ruprecht J., Vorreiter C., Rast S., Zhang L., Schiedel M., Sippl W., Imhof A., Jessen H.J., Einsle O., Schutkowski M., Jung M.,
Angewandte Chemie International Edition 64, e16782-1e16782-8 (2025)
Assembly of face decorated cuboidal cages into ultraporous structures with hierarchical porosity: Accessing MOFs with the awaited red-a topology
Froudas K.G., Tsangarakis C., Montagnon T., Livas C., Klontzas E., Froudakis G.E., Tampaxis C., Charalambopoulou G., Steriotis T.A., Trikalitis P.N.,
Journal of the American Chemical Society 147, 48180-48191 (2025)
Titanium phosphate glasses: Beyond tetrahedral network structures
Girón Lange E., Youngman R.E., Aitken B.G., Ensuncho L., Zeidler A., Hufziger K.T., Lee S.H., Cuello G.J., Eckert H., Salmon P.S.,
Journal of Chemical Physics 163, 244501-1-244501-19 (2025)
Correlating synthesis, structure, and thermal stability of CuBi nanowires for spintronic applications by electron microscopy and in situ scattering methods
Guedeja-Marrón A., Andersen H.L., Sánchez-Santolino G., Zeng L., Ranjan A., Garcia-Manuz I., Fauth F., Dejoie C., Olsson E., Perna P., Varela M., Pérez L., Saura-Múzquiz M.,
ACS Nano 19, 41509-41527 (2025)
A highly selective and versatile probe platform for visualization of monoacylglycerol lipase
Hentsch A., Guberman M., Radetzki S., Kaushik S., Huizenga M., Paul J., Schippers M., Benz J., Kuhn B., Heer D., Topp A., Esteves Gloria L., Walter A., Hochstrasser R., Wittwer M.B., von Kries J.P., Collin L., Blaising J., van der Stelt M., Lipstein N., Grether U., Nazaré M.,
Angewandte Chemie International Edition 64, e202413405-1-e202413405-13 (2025)
Accelerating surface reconstruction in cobalt carbodiimides through structural defects for enhanced oxygen evolution
Huang C., Triana C.A., Jia B., Dongfang N., Erni R., Abbott D.F., Dürr R.N., Zhao H., Mougel V., Iannuzzi M., Patzke G.R.,
ACS Nano 19, 41888-41899 (2025)
Discovery of gut-restricted PRMT5 inhibitors to intercept colorectal cancer in patients with genetic loss of tumor suppressor adenomatous polyposis coli
Hulpia F., Schepens W., Lepri S., Nicolai J., Jiang Z., Boj S.F., Bush T.L., Carvalho M.A., Chen F., Chu G., Clancy K.W., Etwebi Z., Everaerts M., Fan Y., Fernandez Candelaria F.O., Francis A., Hixon M.S., Jardi F., Jin S., Larin E.M., Last S., Leenaerts J.E., Li S., Liddane A.G., Lutter F.H., Lv D., Mattson B., Milligan C.M., Patrick A.N., Patwardhan G.A., Perez-Benito L., Pieters S., Renders E., Retzbach E., Smith-Monroy C., Silva J., Silva M., Sterckx H., ten Hag G., Thate C., Van Brandt S., Verissimo C.S., Verniest G., Vesely E., Vetrano I., Vinken P., Wang Y., Wong V., Yao X., Yang J., Zijlmans R., Bachman K.E., Pocalyko D., Jimenez J.M., Gaffney D., Thuring J.W.,
Journal of Medicinal Chemistry 68, 23825-23866 (2025)
A whole-organ multi-scale in silico framework for human kidney haemodynamics informed by hierarchical phase-contrast tomography
Javanmardi Y., Lyu M., Zhou Y., Wang Y., Walsh C.L., Tafforeau P., Jafree D.J., Long D.A., Bellier A., Torii R., Lee P.D.,
BioRxiv , 1-24 (2025)
Octahedral iron in catalytic sites of endonuclease IV from Staphylococcus aureus and Escherichia coli
Kirillov S., Isupov M., Paterson N.G., Wiener R., Abeldenov S., Saper M.A., Rouvinski A.,
Biochemistry 64, 67-82 (2025)
A new caridean shrimp fossil with exceptionally preserved organs from the Middle Jurassic of La Voulte-sur-Rhône, France
Lagrange F., Audo D., Odin G.P., De Grave S., Fernandez V., Dollman K., Charbonnier S.,
Acta Palaeontologica Polonica 70, 775-794 (2025)
How does a delicate insect wing resist damage? Chitin orientation is adapted to the mechanical demands at the nanoscale
Li C., Liu J., Burghammer M., Wan C., Gorb S.N., Schaber C.F.,
Advanced Materials 37, e03941-1-e03941-13 (2025)
Sustainable recovery and reuse of hard carbon from scrap and end‐of‐life sodium‐ion batteries
Liu B., Song T., Chen L., Shekhar A.T., Mirolo M., Vinci V., Drnec J., Cornelio J., Xie D., Driscoll E.H., Slater P.R., Kendrick E.,
Advanced Energy Materials 15, 2405894-1-2405894-13 (2025)
Shear‐induced supramolecular organization of calf‐thymus DNA in solution: Insights from SAXS coupled with rheology
Lopez Alvarez S., Toriz G., Soltero Martinez J. F. Armando, Saint-Jalmes A., Roux D., Nallet F., Rinaudo M., Bravo-Anaya L.,
Macromolecular Symposia 414, e70243-1-e70243-4 (2025)
Dynamic self-assembly and stimuli-responsive disassembly of bioactive-loaded cubosomes in biomimetic media traced by real-time small-angle X-ray scattering and cryogenic transmission electron microscopy
Madrid R.R.M., Angelova A., Angelov B., Manna G., Mathews P.D., Mertins O.,
ACS Applied Materials & Interfaces 17, 69118-69133 (2025)
The role of stretching-induced phase transformations in the mechanical properties of isotactic 1-butene-ethylene copolymers from Ziegler–Natta catalyst
Malafronte A., Di Girolamo R., Giordano A., De Stefano F., Scoti M., De Rosa C.,
Macromolecules 58, 13252-13266 (2025)
Lability of uranium in a mine-impacted wetland 70 years after the contamination
Montavon G., Nivesse A.L., Martin A., Arnold T., Sachs S., Bok F., Scheinost A.C., Stumpf T., Coppin F., Gourgiotis A., Del Nero M., Chardon P., Landesman C.,
Environmental Science and Technology 59, 26661-26671 (2025)
Computational platforms for deciphering Ancient Greek papyrus fragments
Mshvidobadze T.,
Caucasus Journal of Social Sciences 18, 98-107 (2025)
ANV600 is a novel PD-1 targeted IL-2Rβγ agonist that selectively expands tumor antigen-specific T cells and potentiates PD-1 checkpoint inhibitor therapy
Murer P., Petersen L., Egli N., Salazar U., Neubert P., Zurbach A., Rau A., Stocker C., Reichenstein D., Katopodis A., Huber C.,
Journal for Immunotherapy of Cancer 13, e011905-1-e011905-13 (2025)
Structural and functional features of Klebsiella pneumoniae capsular degradation by the phage depolymerase KP32gp38: implications for vaccination
Napolitano V., Privitera M., Drulis-Kawa Z., Marasco D., Fallarini S., Berisio R., Squeglia F.,
International Journal of Antimicrobial Agents 66, 107596-1-107596-12 (2025)
Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimization
Nippa D.F., Atz K., Stenzhorn Y., Muller A.T., Tosstorff A., Benz J., Binch H., Burkler M., Haider A., Heer D., Hochstrasser R., Kramer C., Reutlinger M., Schneider P., Shema T., Topp A., Walter A., Wittwer M.B., Wolfard J., Kuhn B., van der Stelt M., Martin R.E., Grether U., Schneider G.,
Nature Communications 16, 11646-1-11646-12 (2025)
Structural elucidation and covalent modulation of the autorepressed orphan nuclear receptor NR2F6
Oerlemans GJM, van den Oetelaar MCM, van den Elzen S.P., Brunsveld L.,
ACS Chemical Biology 20, 2308-2317 (2025)
Bipartite binding of the intrinsically disordered scaffold protein JIP1 to the kinase JNK1
Orand T., Delaforge E., Lee A., Kragelj J., Tengo M., Tengo L., Blackledge M., Boeri Erba E., Davis R.J., Palencia A., Jensen M.R.,
Proceedings of the National Academy of Sciences of the USA 122, e2419915122-1-e2419915122-12 (2025)
Targeting TAZ-TEAD in minimal residual disease enhances the duration of targeted therapy in melanoma models
Ott C.A., Purwin T.J., Chen P.Y., Chowdhury S., Mellor G.L., Luo K., Mersky G.L., Tiago M., Madden W.D., Varney S.D., Erkes D.A., Lamar J., Capparelli C., Bollag G., Aplin A.E.,
Nature Communications 16, 9655 (2025)
STX-721, a covalent EGFR/HER2 exon 20 inhibitor, utilizes exon 20-mutant dynamic protein states and achieves unique mutant selectivity across human cancer models
Pagliarini R.A., Henderson J.A., Milgram B.C., Borrelli D.R., Brooijmans N., Hilbert B.J., Huff M.R., Ito T., Kryukov G.V., Ladd B., Martin B.R., Motiwala H., O'Hearn E., Tsai C.F., Wang W., Bellier J., Boland L., Clark S., Hensley E., Hata A.N., Kuzmic P., Guzman-Perez A., Jackson E.L., Stuart D.D.,
Clinical Cancer Research 31, 3002-3018 (2025)
Insights into the self-assembly and interaction of sars-cov-2 fusion peptides with biomimetic plasma membranes
Pawar N., Santamaria A., Romano B., Batchu K.C., Laux V., Guzmán E., Zaccai N.R., Alvarez-Fernandez A., Maestro A.,
Nature Communications , epub (2025)
Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition
Petzold G., Gainza P., Annunziato S., Lamberto I., Trenh P., McAllister L.A., DeMarco B., Schwander L., Bunker R.D., Zlotosch M., SriRamaratnam R., Gilberto S., Langousis G., Donckele E.J., Quan C., Strande V., De Donatis G.M., Alabi S.B., Alers J., Matysik M., Staehly C., Dubois A., Osmont A., Garskovas M., Lyon D., Wiedmer L., Oleinikovas V., Lieberherr R., Rubin N.T., Lam D.T., Lucas X., Liardo E., Widlund N.I., Ritzen A., Caceres R.M., Vigil D., Tsai J., Wallace O., Peluso M., Sadok A., Tiedt R., Paterson A.M., Zarayskiy V., Fasching B., Bonenfant D., Warmuth M., Castle J.C., Townson S.A.,
Science 389, eadt6736-1-eadt6736-19 (2025)
Disorder-driven relaxor-ferromagnetic transition in samarium and cobalt co-doped BiFeO3 ceramics
Raman R., Nambi Venkatesan G., Sankar R.,
Physica Scripta 100, 125968-1-125968-20 (2025)
The Heterogeneous Nature of Atrioventricular Conduction Tissues in Tetralogy of Fallot demonstrated by Hierarchical Phase-contrast Tomography – redefining the anatomic substrate
Sabarigirivasan V., Brunet J., Dejea H., Crucean A., Jegatheeswaran A., Capelli C., Pajaziti E., Urban T., Purzycka J., Tafforeau P., Walsh C.L., Lee P.D., Cook A.C.,
BioRxiv , 1-29 (2025)
Crystalline order yet glass-like heat transport driven by hidden local distortions as the structural origin of ultralow thermal conductivity in AgErTe2
Sarkar D., Shahabfar S., Liu Y., Yanda P., Ie T.S., Zhao H., Nandi P., Pradeep K.R., Shekhar C., Felser C., Dravid V.P., Wolverton C.M., Kanatzidis M.G.,
Journal of the American Chemical Society 147, 46483-46496 (2025)
Phonons in epitaxial DySi2: From the bulk to self-organized nanoislands and nanowires
Stankov S., Piekarz P., Seiler A., Merkel D.G., Bauder O., Pradip R., Baumbach T.G., Chumakov A. I., Rüffer R.,
Physical Review Letters 135, 256202-1-256202-8 (2025)
Lead, locked away: Porous Zr–phytate coordination polymers for rapid and selective removal of Pb2+ from water
Taheri N., Schertenleib T., Felder T.M.O., Piveteau L., Mouriño B., Smit B., Nazeeruddin M.K., Queen W.L.,
Journal of the American Chemical Society 147, 45936-45950 (2025)
Single-determinant ground state in Ce4+ imidophosphorane complexes
Tateyama H., Liao C., Wilkinson G.R., Ramanathan A., Amidani L., Bazarkina E., Ressnik F., Engle K.S., Bacsa J., Sokaras D., Kvashnina K.O., Li X., La Pierre H.S.,
Inorganic Chemistry 64, 24401-24410 (2025)
Dislocations influence the background hole densities in Ge/Si virtual substrates
Tetzner H., Corley-Wiciak A.A., Devaiya A.J., Concepción O., Stolarek D., Schubert M.A., Yamamoto Y., Buca D., Capellini G.,
Applied Physics Letters 127, 251901-1- 251901-6 (2025)
Prediction and analysis of symmetry-raising transitions in anilinium tetrafluoroborate
Thompson S.Y., Fuller C.A., Page S.J., Bell A.J., Evans J.S.O.,
Acta Crystallographica B 81, 587-594 (2025)
The oxidized Ti2(Al/Sn)C behavior as anode for lithium‐ and sodium‐ion batteries: The role of the MAX phase order
Vallana N., Ostroman I., Marchionna S., Palladini C., Gentile A., Perego O., Sheptyakov D., Fitch A., Ferrara C., Ruffo R.,
ChemElectroChem 12, e202400712-1-e202400712-8 (2025)
Discovery of NP3-742: A structurally diverse NLRP3 inhibitor identified through an unusual phenol replacement
Velcicky J., Langlois J.B., Wright M., Janser P., Angst D., Arnold C., Beltz K., Brenneisen S., Dubois C., Dawson J., Fischer C., Gommermann N., Heizmann A., Ilic S., Machauer R., Maschlej M., Monnerat S., Pflieger D., Ristov J., Rubert J., Schwalm G., Smith D.R., Srinivas H., Steiner R., Stojanovic A., Troxler T., Unterreiner A., Vangrevelinghe E., von Burg N., Wunderlich J., Farady C.J., Mackay A.,
Journal of Medicinal Chemistry 68, 23532-23553 (2025)
Rational design of antibodies with pH-dependent antigen-binding properties using structural insights from broadly neutralizing antibodies against α-neurotoxins
Wade J., Strancar N., Fernández-Quintero M.L., Siebenhaar S., Jansen T., Meier E.P.W., Jenkins T.P., Bjørn S.P., Nguyen G.T.T., Lomonte B., Gutiérrez J.M., Sørensen C.V., Loeffler J.R., Paul A., Tulika T., Arnsdorf J., Schoffelen S., Lundquist E.V.S., Sørensen J., Ward A.B., Voldborg B.G., Bohn M.F., Rivera-de-Torre E., Morth J.P., Laustsen A.H.,
mAbs 17, 2553624-1-255362424 (2025)
Right-handed chiral photonic cellulose nanocrystal films
Wei L., Zhou L., Chen P., Wang X., Ogawa Y., Nishiyama Y., Xu Y.,
ACS Nano 19, 42941-42950 (2025)
Identifying and mitigating adverse X-ray induced effects in operando spectroscopic studies of copper exchanged zeolites
Wieser J., Newton M.A., Rzepka P., Leidinger P.M., Ramakrishnan M., Just J., van Bokhoven J.A.,
Journal of Physical Chemistry C 129, 22191-22201 (2025)
Pseudouridine increases ribosome stability in a thermophilic eukaryote
Wild K., Klein M., Burkard A., Marchand V., Kellner N., Paez A., Pastore S., Butto T., Motorin Y., Helm M., Sinning I.,
Nucleic Acids Research 53, gkaf1368-1-gkaf1368-19 (2025)
Fast scanning small angle X-ray scattering of hydrated biological cells
Yu B., Sinha M., Da Silva R.M., Rolleke U., Burghammer M., Köster S.,
BioRxiv , 1-18 (2025)
Modulator control of cation distribution in mixed-metal UiO-66(Zr,Ce) metal-organic frameworks
Zhao B., Hutereau M., Walker M., Kashtiban R.J., Thompson P.B.J., Slater B., Walton R.I.,
Chemistry of Materials 37, 9676-9688 (2025)
Mechanistic and structural insights into the itaconate-producing trans-aconitate decarboxylase Tad1
Zheng L., Li W., Christ M., Paczia N., Buckel W., Mais C.N., Bolker M., Freitag J., Bange G.,
PNAS Nexus 4, pgaf059-1-pgaf059-9 (2025)
Perfluoroarene‐based tin halide perovskite photovoltaics
Zhu M., Singh S., Castro Chong A.M., Kim J.M., Koc F., Panda D.P., Zimmermann P., Hinderhofer A., Luo W., AlSabeh G., Ur Rehman M.O., Choi G., Chernyshov D., Schreiber F., Seo J.Y., Vaynzof Y., Abate A., Milic J.V.,
Advanced Energy and Sustainability Research 6, 2500028-1-2500028-8 (2025)
In situ X-ray synchrotron studies reveal the nucleation and topotactic transformation of iron sulfide nanosheets
Zito C.A., Klemeyer L., Caddeo F., Jessen B., Harouna-Mayer S.Y., Lacroix L.M., Langfeldt M., Gröne T.L.R., Kesavan J.K., Hsu C.S., Schwarz A., Dippel A.C., Igoa Saldaña F., Detlefs B., Koziej D.,
Journal of the American Chemical Society 147, 47409-47420 (2025)