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Latest publications

Displayed below is a list of the latest publications that have been added - in the last ten days -  to the library database of peer-reviewed journal articles arising from ESRF experiments, an RSS feed of this list can be subscribed to.

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For the full list of publications, please visit the library web site.
 

New ESRF publications

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Glutamate indicators with increased sensitivity and tailored deactivation rates

Aggarwal A., Negrean A., Chen Y., Iyer R., Reep D., Liu A., Palutla A., Xie Michael E., MacLennan Bryan J., Hagihara Kenta M., Kinsey Lucas W., Sun Julianna L., Yao P., Zheng J., Tsang A., Tsegaye G., Zhang Y., Patel Ronak H., Arthur Benjamin J., Hiblot J., Leippe P., Tarnawski M., Marvin Jonathan S., Vevea Jason D., Turaga Srinivas C., Tebo Alison G., Carandini M., Rossi L. Federico, Kleinfeld D., Konnerth A., Svoboda K., Turner Glenn C., Hasseman Jeremy P., Podgorski K.,
Nature Methods , epub (2025)

Magnetic excitations of a half-filled Tl-based cuprate

Bialo I., Wang Q., Küspert J., Hong X., Martinelli L., Gerguri O., Chan Y., von Arx K., Forslund O.K., Pudelko W.R., Lin C., Plumb N.C., Sassa Y., Betto D., Brookes N.B., Rosmus M., Olszowska N., Watson M.D., Kim T.K., Cacho C., Horio M., Ishikado M., Rønnow H.M., Chang J.,
Communications Materials , epub (2025)

Discovery of BI-2493, a pan-KRAS inhibitor showing in vivo efficacy

Broker J., Waterson A.G., Hodges T.R., Abbott J.R., Arnold A., Böttcher J., Braun N., Cui J., Fuchs J.E., Gerstberger T., Gogg S., Hanner S., Herdeis L., Howell L.W., Mantoulidis A., Mayer M., Phan J., Rocchetti F., Sankar K., Sarkar D., Schaaf O., Sensintaffar J.L., Sun Q., Wunberg T., Fesik S.W.,
Journal of Medicinal Chemistry 68, 15649-15668 (2025)

Discovery of gut-restricted PRMT5 inhibitors to intercept colorectal cancer in patients with genetic loss of tumor suppressor adenomatous polyposis coli

Hulpia F., Schepens W., Lepri S., Nicolai J., Jiang Z., Boj S.F., Bush T.L., Carvalho M.A., Chen F., Chu G., Clancy K.W., Etwebi Z., Everaerts M., Fan Y., Fernandez Candelaria F.O., Francis A., Hixon M.S., Jardi F., Jin S., Larin E.M., Last S., Leenaerts J.E., Li S., Liddane A.G., Lutter F.H., Lv D., Mattson B., Milligan C.M., Patrick A.N., Patwardhan G.A., Perez-Benito L., Pieters S., Renders E., Retzbach E., Smith-Monroy C., Silva J., Silva M., Sterckx H., ten Hag G., Thate C., Van Brandt S., Verissimo C.S., Verniest G., Vesely E., Vetrano I., Vinken P., Wang Y., Wong V., Yao X., Yang J., Zijlmans R., Bachman K.E., Pocalyko D., Jimenez J.M., Gaffney D., Thuring J.W.,
Journal of Medicinal Chemistry 68, 23825-23866 (2025)

STX-721, a covalent EGFR/HER2 exon 20 inhibitor, utilizes exon 20-mutant dynamic protein states and achieves unique mutant selectivity across human cancer models

Pagliarini R.A., Henderson J.A., Milgram B.C., Borrelli D.R., Brooijmans N., Hilbert B.J., Huff M.R., Ito T., Kryukov G.V., Ladd B., Martin B.R., Motiwala H., O'Hearn E., Tsai C.F., Wang W., Bellier J., Boland L., Clark S., Hensley E., Hata A.N., Kuzmic P., Guzman-Perez A., Jackson E.L., Stuart D.D.,
Clinical Cancer Research 31, 3002-3018 (2025)

Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition

Petzold G., Gainza P., Annunziato S., Lamberto I., Trenh P., McAllister L.A., DeMarco B., Schwander L., Bunker R.D., Zlotosch M., SriRamaratnam R., Gilberto S., Langousis G., Donckele E.J., Quan C., Strande V., De Donatis G.M., Alabi S.B., Alers J., Matysik M., Staehly C., Dubois A., Osmont A., Garskovas M., Lyon D., Wiedmer L., Oleinikovas V., Lieberherr R., Rubin N.T., Lam D.T., Lucas X., Liardo E., Widlund N.I., Ritzen A., Caceres R.M., Vigil D., Tsai J., Wallace O., Peluso M., Sadok A., Tiedt R., Paterson A.M., Zarayskiy V., Fasching B., Bonenfant D., Warmuth M., Castle J.C., Townson S.A.,
Science 389, eadt6736-1-eadt6736-19 (2025)

Discovery of NP3-742: A structurally diverse NLRP3 inhibitor identified through an unusual phenol replacement

Velcicky J., Langlois J.B., Wright M., Janser P., Angst D., Arnold C., Beltz K., Brenneisen S., Dubois C., Dawson J., Fischer C., Gommermann N., Heizmann A., Ilic S., Machauer R., Maschlej M., Monnerat S., Pflieger D., Ristov J., Rubert J., Schwalm G., Smith D.R., Srinivas H., Steiner R., Stojanovic A., Troxler T., Unterreiner A., Vangrevelinghe E., von Burg N., Wunderlich J., Farady C.J., Mackay A.,
Journal of Medicinal Chemistry 68, 23532-23553 (2025)

Rational design of antibodies with pH-dependent antigen-binding properties using structural insights from broadly neutralizing antibodies against α-neurotoxins

Wade J., Strancar N., Fernández-Quintero M.L., Siebenhaar S., Jansen T., Meier E.P.W., Jenkins T.P., Bjørn S.P., Nguyen G.T.T., Lomonte B., Gutiérrez J.M., Sørensen C.V., Loeffler J.R., Paul A., Tulika T., Arnsdorf J., Schoffelen S., Lundquist E.V.S., Sørensen J., Ward A.B., Voldborg B.G., Bohn M.F., Rivera-de-Torre E., Morth J.P., Laustsen A.H.,
mAbs 17, 2553624-1-255362424 (2025)

Perfluoroarene‐based tin halide perovskite photovoltaics

Zhu M., Singh S., Castro Chong A.M., Kim J.M., Koc F., Panda D.P., Zimmermann P., Hinderhofer A., Luo W., AlSabeh G., Ur Rehman M.O., Choi G., Chernyshov D., Schreiber F., Seo J.Y., Vaynzof Y., Abate A., Milic J.V.,
Advanced Energy and Sustainability Research 6, 2500028-1-2500028-8 (2025)