Synopsis
ID23-2 is a fixed energy beamline dedicated to MX. ID23-2 offers a standard MX sample environment, but with a focused microbeam (10x4 micron).
Status:
open
Disciplines
Applications
- Macromolecular crystallography
Techniques
-
MX - macromolecular crystallography
-
Microbeam
Beam size
- Minimum (H x V) : 1.0
x 2.0
µm²
-
Maximum (H x V) : 8.0
x 25.0
µm²
Sample environments
- Microdiffractometer MD3Up
- UNIPUCK+SPINE pins only (no SC3)
Detectors
Technical details
This beamline offers diffraction data collection on microcrystalline MX samples and on fine needle MX samples, as well as determination of the region of highest diffraction quality from larger MX samples.
ID23-2: an automated and high-performance microfocus beamline for macromolecular crystallography at the ESRF
Protein‐tags and their fragments as potent inhibitors of enzymes: Structure of the ternary complex of phosphopantetheine adenylyltransferase from Enterobacter spp. with tag‐peptides and phosphonoacetic acid at 2.20 Å resolution
Ahmad N., Kumar V., Goel V.K., Sharma P., Sharma S., Singh T.P.,
Protein Science 34, e70216-1-e70216-18 (2025)
The mechanism of pathogenic α1-antitrypsin aggregation in the human liver
Aldobiyan I., Elliston E.L.K., Heyer-Chauhan N., Arold S.T., Zhao L., Huntington B., Lowen S.M., Orlova E.V., Irving J.A., Lomas D.A.,
Proceedings of the National Academy of Sciences of the USA 122, e2507535122-1-e2507535122-10 (2025)
Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse
Bansard L., Laconde G., Delfosse V., Huet T., Ayeul M., Rigal E., Donati Q., Gerbal-Chaloin S., Daujat-Chavanieu M., Brunel L., Legrand B., Chavanieu A., Martin A.R., Pannequin J., Bourguet W., Amblard M., Pascussi J.M.,
Oncogenesis 14, 34-1-34-15 (2025)
Altering substrate specificity of a thermostable bacterial monoamine oxidase by structure-based mutagenesis
Basile L., Poli C., Santema L.L., Lesenciuc R.C., Fraaije M.W., Binda C.,
Archives of Biochemistry and Biophysics 764, 110276-1-110276-7 (2025)
A scaffold for quinone channeling between membrane and soluble bacterial oxidoreductases
Broc M., Cherrier M.V., Uzel A., Arias-Cartin R., Arnoux P., Brasseur G., Seduk F., Guigliarelli B., Legrand P., Pierrel F., Schoehn G., Maté M.J., Martin L., Grimaldi S., Nicolet Y., Magalon A., Walburger A.,
Nature Structural & Molecular Biology 32, 2196-2202 (2025)
Investigating the structure-activity-relationship of diaryl ether-based paFabV inhibitors: A path to novel antibacterials
Bulai R.G., Van Eynde W., Heylen S., Cremonini M., Van Olmen F., Wicik R., Lescrinier E., Rozenski J., Voet A., Masschelein J., Verwilst P.,
European Journal of Medicinal Chemistry 296, 117782-1-117782-31 (2025)
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