Detailed programme

Structural and Molecular Biology
of
Host-Pathogen Interactions

5-6-7 February, 2008
Venue: ESRF Auditorium

TUESDAY February 5th, 2008
11:00-12:00	Registration
*12:00-13:30 Lunch at the ESRF restaurant*
Session 1 BACTERIAL ADHESION Chair: Andrea Dessen
13:30-13:40	Introduction by Sine Larsen, ESRF, Director of Research
13:40-14:20	The chaperone-usher pathway of pilus biogenesis: structural basis of the assembly process of host recognition	Gabriel Waksman ISMB London, UK
14:20-14:45	Atomic resolution basis for host cell recognition by apicomplexan parasites and pathogenic bacteria	Stephen Matthews Imperial College London, UK
14:45-15:10	Function and Assembly of Type IV secretion systems	Eric Cascales IBSM, Marseille, France
*15:10-15:30 Coffee break*
Chair: Laurent Terradot
15:30-16:10	Assembly of the Yersinia Ysc Injectisome	Guy Cornelis University of Basel, Basel, Switzerland
16:10-16:35	Regulation of type III secretion needle formation in Pseudomonas aeruginosa	Andrea Dessen IBS, Grenoble, France
16:35-17:00	Instabilities and irregularities promote virulence in Group A Streptococcus M1 protein	Partho Gosh University of California, San Diego, USA
*17:00-17:20 Coffee break*
Session 2 VIRUS AND HOST CELL FACTORS Chair: Winfried Weissenhorn
17:20-18:00	HIV assembly in monocytic cells	Mark Marsh MRC Cell Biology Unit, London, UK
18:00-18:25	Assembly of ESCRT machinery on membranes and disassembly by Vps4 AAA-ATPase	Olga Perisic MRC Laboratory for Molecular Biology, Cambridge, UK
18:25-18:30	Concluding remarks
*18:30- 19:30 POSTER SESSION & Aperitif*
*19:45 Bus departure from the ESRF to the restaurant*
*20:00 Workshop dinner at the Restaurant Novotel*
*22:00 Bus departure from the restaurant to the ESRF Guesthouse*
WEDNESDAY February 6th, 2008
09:00-12:00	ESRF Users' Meeting Plenary Session
*12:00-13:30 Lunch at the ESRF restaurant*
13:30-15:00	MX Parallel Session
Session 2bis VIRUS AND HOST CELL FACTORS Chair: Dominique Housset
15:20-16:00	Ligand Recognition and Plasticity in HIV Envelope Glycoprotein gp120	Wayne Hendrickson Columbia University, New York, USA
16:00-16:25	Structural insights into the function of the PB2 subunit of influenza virus polymerase	Stephen Cusack EMBL, Grenoble, France
*16:25-16:55 Coffee break*
Chair: Daniel Panne
16:55-17:20	Structural Analysis of Virus-Receptor Interactions	Thilo Stehle Universität Tübingen, Tübingen, Germany
17:20-17:45	Structural Enigmas Concerning Transcription and Replication of Rabies Virus	Robert Ruigrok UJF-EMBL-CNRS, Grenoble, France
17:45-18:25	Plenary 6	Dave Stuart MRC Structural Biology, Oxford, UK
18:25-18:30	Concluding remarks
*18:30- 19:50 POSTER SESSION & Aperitif*
20:00-22:30 Users' Meeting Dinner (Transport will be organized at 22:30 from the ESRF to downtown Grenoble)
THURSDAY February7th, 2008
Session 3 IMMUNE RESPONSE Chair: Gérard Arlaud
09:00-09:45	The central steps of the Complement System	Piet Gros Bijvoet Center of Biomolecular Research, Utrecht, The Netherlands
09:45-10:10	TRIM21: A novel mammalian IgG-receptor that mediates autoimmune disease	Leo James MRC Laboratory of Molecular Biology, Cambridge, UK
10:10-10:35	The Structural Basis of T-Cell Receptor Recognition	Craig Clements Monash University, Clayton, Australia
*10:35-10:50 Coffee break*
Chair: Stephen Cusack
10:50-11:35	Mutliple roles of Peptidoglycan Recognition proteins in Drosophila	Bruno Lemaitre Global Health Institute, Lausanne, Switzerland
11:35-12:00	An atomic model of INF-b enhanceosome structure	Daniel Panne EMBL, Grenoble, France
12:00-12:40	Plenary 4	John Skehel MRC National Institute for Medical Research, London, UK
12:40-12:45	Concluding remarks	Stephen Cusack EMBL, Grenoble, France