4th Winter School on Soft X-rays in Macromolecular Crystallography
Dates: 6-7-8 February 2012
Venue: CIBB Seminar Room
Organisers:
C. Müller-Dieckmann, ESRF, Grenoble, France
G. Leonard, ESRF, Grenoble, France
K. Djinovic-Carugo, University Departments at the Vienna Biocenter, Austria
M. Weiss, Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Germany

 
Administrative Assistant: Eva Jahn (ESRF)
Contact Organisers:
e-mail 
 

 

 

Aim of the Workshop

An increasing number of new crystal structures of biological macromolecules structures are solved exploiting anomalous signals available at longer wavelengths. The main advantage of using longer wavelengths is that the anomalous signal from innate sulphur, phosphorous or other light atoms (e.g. Ca, K, Cl) can be used to obtain phasing information, thus obviating the need to prepare the derivative crystals usually used in macromolecular crystal structure solution. However, at longer wavelengths currently routinely accessible, such anomalous signals are rather small (usually ~ 1%).  Special care must thus be given to experimental setups and data collection protocols. This workshop brings together experts in the hardware and software required to successfully perform such experiments. The following topics will be covered:

 

  • Optimised experimental setups for diffraction data collection at longer wavelengths
  • Advanced data collection strategies, taking into account radiation damage
  • Optimised of data processing protocols for longer wavelength experiments
  • Anomalous scattering substructure determination using longer wavelength data

 

The School will last for three days in all - straddling the ESRF Users' Meeting - and consists of 1,5 days of lectures. The number of participants will be limited to 20.

 

Programme

 

Costs met by the ESRF:

  • Accommodation in the guesthouse on site
  • Workshop dinner & Poster session buffet

Costs met by the participants:

  • registration fee of 150 € (including attendance of Users' Meeting & Workshops, meals, coffee breaks, Users' Meeting Dinner)
  • travel expenses

    

Applications for participation in the Winter School should include:

  • a letter of motivation
  • C.V.
  • a recommendation letter from the supervisor
  • an abstract of the poster which would be presented at the Winter School/ESRF Users' Meeting.

 and be sent to the Winter School e-mail address by Monday 12th December

 

 

Important Dates

 

Deadline for applications: 12 December 2011

 

Notification of acceptance for your application: 16 December 2011

 

Deadline for Registration, Abstracts, request for accommodation: 19 January 2012

(150€ until 19 January, 200€ from 20 until 24 January)

 

  

Speakers

 

  • M. Cianci, EMBL Hamburg, Germany
  • K. Djinovic-Carugo, Vienna Biocenter, Austria
  • D. de Sanctis, ESRF, Grenoble, France
  • P. Johansson, AstraZeneca Strcutural Chemistry Laboratory, Molndal, Sweden
  • J. Liu, National Laboratory of Biomacromolecules, Beijing, China
  • R. Giordano, ESRF, Grenoble, France
  • G. Leonard, ESRF, Grenoble, France
  • C. Mueller-Dieckmann, ESRF Grenoble
  • J. Pflugrath, Rigaku, USA
  • A. Popov, ESRF, Grenoble, France
  • I. Uson, IBMB-CSIC, Barcelona, Spain
  • A. Wagner, Diamond Light Source, UK
  • B.C. Wang, University of Georgia, USA
  • M. Wang, Swiss Light Source Villigen, Switzerland
  • M.S. Weiss, Helmholtz-Zentrum für Materialien und Energie, Germany